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Tackling Salmonella Epidemics in Poultry Using “Angel’s Glow”

2021 CPRF
Historically, “Angel’s Glow” was referred to wounds which glow in the dark of soldiers who battled during the American Civil War (1861 -1865). Wounds were contaminated with bacteria that produced a light signal and this phenomenon is known as bioluminescence. Bioluminescence can be transferred into other “dark” bacteria like Salmonella to unveil host-pathogen interactions and accelerate therapeutic discovery. We generated glowing Salmonella Enteritidis strains that enabled us to track them while inside the poultry host. Further, the technology facilitated to investigate some of the putative virulence determinants of Salmonella which enable them to survive inside the avian host. Here we will be discussing some of those findings and how the technology can be utilized to minimize future Salmonella epidemics in the poultry industry.
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PhD Candidate

Vaccine and Infectious Disease Organization

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